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Microencapsulation for the Therapeutic Delivery of …

Both free and microencapsulated islets responded to glucose challenge in static incubation and perifusion by significantly increasing their rate of insulin release and theophylline significantly potentiated the insulin response to glucose.

Otherwise, the microencapsulated cells should be kept viable in continuous culture conditions.

Therefore, microencapsulation using spray drying has been used as an effective method for protecting probiotics from harsh environments and controlled release at desired conditions increasing the applicability of probiotics in various food products.

Bioencapsulation Research Group

Therefore, the objectives of this study was to 1) evaluate the effect of atomization methods on survivability of bacterial cells during microencapsulation process and storage and 2) evaluate the effect of microencapsulation on viability of selected probiotics for storage and simulated gastrointestinal tract.

implantation of microencapsulated islets into STZ-diabetic recipients, revealed that the inclusion of islets within microcapsules increased their immunogenicity and markedly increased the extent of pericapsular fibrosis.

KNUST Graduate programs - 2018/2019

(2014) Novel processing and microencapsulation of Ganoderma Lucidum spores for healthcare. Doctoral thesis , UCL (University College London).

Low concentrations of NG-monomethyl L-arginine (L-NMMA) had no significant effect on glucose stimulated insulin release from either free or microencapsulated islets.

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6th International Congress on Food Technology

Background and Objectives: Probiotics including strains of Lactobacillus spp. are living microorganisms including which are beneficial to human and animals health. In this study, Lactobacillus has been isolated from corn silage in a cold region of Iran by anaerobic culture.
Materials and Methods: The bacteriological and biochemical standard methods were used for identification and phenotypic characterization of isolated organism. To increase the stability of organism in the environment, we used microencapsulation technique using stabilizer polymers (Alginate and Chitosan).
Results: The isolated Lactobacillus spp. was able to ferment tested carbohydrates and grow at 10°C -50°C. Using microencapsulation, the stability and survival of this bacterium increased.
conclusion: microencapsulation of lactic acid bacteria with alginate and chitosan coating offers an effective way of delivering viable bacterial cells to the colon and maintaining their survival during refrigerated storage.

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The outer alginate layer created a significant barrier to glucose/insulin exchange and reduced the insulin responsiveness of microencapsulated islets to glucose.

Program | 6th World Congress and Expo on …

Mortazavian A Razavi SH, Ehsani MR, Sohrabvandi S. Principles and methods of microencapsulation of probiotic microorganism. Iranian J Biotech. 2007; 5:1-18.

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Micro-encapsulation: Types of microcapsules, importance of microencapsulation in pharmacy, microencapsulation by phase separation, coacervation, multi-orifice, spray drying, spray congealing, polymerization complex emulsion, air suspension technique, coating pan and other techniques, evaluation of micro capsules.

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Na+ -alginate-PLO-alginate microencapsulated islets were significantly more responsive to elevated glucose than Na+ -alginate-PLL-alginate microencapsulated islets, due to the enhanced porosity of PLO membranes.

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