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Thesis Obesity Ospital – 537773

In this course we learn about the pathological changes caused by microbial infections (virus, bacteria and fungus) or toxic materials which induce tissue damage. Then we learn that our immune system recognizes them using receptors, eradicates microbes and repairs damaged tissues. Specific microbes such as hepatitis C and continued or carcinogenetic stimuli can overcome the immune system and lead to tissue failure or the development of cancer.

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Dr. Kevin Foley completed his PhD in the department of Biochemistry at the University of Toronto studying mechanisms regulating the intracellular sorting of GLUT4 in muscle cells under the supervision of Dr. Amira Klip. His current postdoctoral research under the supervision of Dr. Jonathan Schertzer at McMaster University involves studying how NOD proteins link inflammation to obesity-induced insulin resistance.

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Subclinical atherosclerosis in children with obesity enrolled in weight management

Julian completed his BSc in the Biology & Pharmacology Program at McMaster University and is now a PhD student under the supervision of Dr. Gregory Steinberg. His dissertation focuses on exploring sources of peripheral serotonin that mediate the progression of metabolic diseases such as obesity and type II diabetes.

Dr. Scott Widenmaier is a post-doctoral fellow in the Department of Genetics and Complex Diseases and the Sabri Ulker Center for Metabolic Research at the Harvard TH Chan School of Public Health, under the supervision of Professor Gokhan Hotamisligil MD, PhD. His research is focused on delineating how mammalian adaptive systems defend against nutrient challenges to guard metabolic homeostasis. In this talk, he will describe the recent discovery by Dr. Alex Bartelt, himself, and Dr. Hotamisligil that an endoplasmic reticulum localized transcription factor named Nrf1 plays a central role in securing homeostatic control of metabolism in brown adipose tissue to ensure the needed thermogenic capacity is available when brown adipose is placed under tremendous metabolic burdens, such as cold exposure and obesity.

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Lisa Chu completed her BSc in Kinesiology at McMaster University and went on to complete her MSc at York University. There, she worked with a collaborative childhood obesity research team at SickKids hospital. She then returned to McMaster for her PhD in Medical Sciences under the supervision of Dr. Brian Timmons. Her thesis focuses on metabolic flexibility during exercise in children.

Adeola Ishola completed her BSc at McMaster University in Biology and is currently completing her MSc in Medical Science under the supervision of Dr. David Meyre. Her thesis examines the pleiotropic effect of obesity predisposing genes on metabolic complications in multiethnic populations.

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Thesis For Personal Essays -- Thesis Of Diesel Engine

Professor Julie Glowacki, Ph.D. is Director of the Skeletal Biology Research Laboratory, which studies basic, clinical, and translational aspects of skeletal pathophysiology, skeletal cell differentiation, effects of age and vitamin D status on bone physiology, mechanisms of chondro/osteoinduction, and tissue engineering approaches for skeletal regeneration. The group studies human bone and cartilage cell differentiation with marrow tissues that are discarded during orthopedic surgery. They have discovered that different aspects of in vitro cell behavior are influenced by age, gender, vitamin D status, obesity, and kidney function of the subject from whom the cells were obtained. The goal is to prevent or reverse bone cell aging by safe and effective means.

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