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Artificial intervertebral disc prosthesis

March 5, 1991. 32. Savchenko et al, Russian Patent 2140229, 1999. 3. Ojima, European Patent 0317972, 1989. 34. Bryan V, Kunzler A, inventor: Human spinal disc prosthesis. US patent 5,865,846, February 2, 1999. 35. Gordon J, inventor: Intervertebral disc replacement prothesis. US

replacement of cervical intervertebral discs with a metal prosthesis.

70. Frey O, Koch R, Planck HMF, inventors: Joint endoprosthesis. US patent 4,932,969, June 12, 1990. 71. Strong MD, inventor: Method of determining the quality of a crimped electrical connection. US patent 5,197,186, March 30, 1993. 72. Baumgartner W, inventor: Intervertebral prosthesis. US patent 5,171,280, December 15, 1992. 73. Fuhrmann G, Gross U, Kaden B, et al, inventors: Intervertebral disk endoprosthesis. US patent 5,002,576, March 26, 1991. 74. Monteiro, Spanish Patent 2094077, 1997. 75. Krapiva PI, inventor: Disc replacement method and apparatus. US patent 5,645,597, July 8, 1997. 76. Gauchet, World Patent 0035387, 2000. 7. Minda and Schmidt, European Patent 1157675, 2001. 78. Weber and Da Silva, World Patent 0190786, 2001. 79. Kennedy JP: From thermoplastic elastomers to designed biomaterials.

Lumbar intervertebral disc prosthesis

J Polymer Sci Part A: Polymer Chemistry 43:2951–2963, 2005. 80. Carl A, Ledet E, Yuan H, Sharan A: New developments in nucleus pulposus replacement technology. Spine J 4:325–329, 2004. 81. Schneider PG, Oyen R: Surgical replacement of the intervertebral disc. First communication: replacement of lumbar discs with siliconrubber. Theoretical and experimental investigations (author's transl). Z Orthop Ihre Grenzgeb 112:1078–1086, 1974. 82. Schneider PG, Oyen R: Proceedings: Disk displacement. Experimental studies—clinical consequences. Z Orthop Ihre Grenzgeb 112:791–792, 1974. 83. Kuntz JD, inventor: Intervertebral disc prosthesis. US patent 4,349,921, September 21, 1982. 84. Marcolongo and Lowman, World Patent 0132100, 2001. 85. Banks, World Patent 0112107, 2001. 86. Kotani Y, Abumi K, Shikinami Y, et al: Artificial intervertebral disc replacement using bioactive three-dimensional fabric: design, development, and preliminary animal study. Spine 27:929–935, 2002. 87. Willert HG: Reactions of the articular capsule to wear products of artificial joint prostheses. J Biomed Mater Res 1:157–164, 1977. 8. Stubstad JA, Urbaniak JR, Kahn P, inventors: Prosthesis for spinal repair. US patent 3,867,728, February 25, 1975. 89. Studer and Schärer, European Patent 1157876, 2001. 90. Duance VC, Crean JK, Sims TJ, et al: Changes in collagen crosslinking in degenerative disc disease and scoliosis. Spine 23:2545–2551, 1998. 91. Crean JK, et al: Matrix metalloproteinases in the human intervertebral disc: role in disc degeneration and scoliosis. Spine 2:2877–2884, 1997. 92. Crevensten G, Walsh AJ, Ananthakrishnan E, et al: Intervertebral disc cell therapy for regeneration: mesenchymal stem cell implantation in rat intervertebral discs. Ann Biomed Eng 32:430–434, 2004. 93. Lotz JC, Kim AJ: Disc regeneration: why, when, and how. Neurosurg Clin N Am 16:657–663, vii, 2005.

Orthop Rel Res 394:139–145, 2002. 5. Nibu K, Panjabi M, Oxland T, Cholewicki J: Multidirectional stabilizing potential of BAK interbody spinal fusion system for anterior surgery. J Spinal Disord 10:357–362, 1997. 56. Bryan V, Kunzler A, inventor: Human spinal disc prosthesis. US patent 5,865,846, February 2, 1999. 57. Bryan et al, World Patent 0013620, 2000. 58. Cauthen JC, inventor: Articulating spinal implant. US patent 6,019,792, February 1, 2000. 59. Mehdizadeh HM, inventor: Disc replacement prosthesis. US patent 6,231,609, May 15, 2001. 60. Patil A, inventor: Artificial intervertebral disc. US patent 4,309,7, January 12, 1982. 61. Dumas et al, French Patent 2734148, 1996. 62. Beer JC, Beer JM, inventors: Synthetic intervertebral disc. US patent 5,458,642, October 17, 1995. 63. Butterman GR, inventor: Intervertebral prosthetic device. US patent 5,827,328, October 27, 1998. 64. Pisharodi M, inventor: Artificial spinal prosthesis. US patent 5,123,926, June 23, 1992. 65. Hedman TP, Kostuik JP, Fernie GR, Maki B, inventors: Artificial spinal disc. US patent 4,759,769, July 26, 1988. 6. Main JA, Wells ME, Keller TS, inventors: Vertebral prosthesis. US patent 4,932,975, June 12, 1990. 67. Froning EC, inventor: Intervertebral disc prosthesis and instruments for locating same. US patent 3,875,595, April 8, 1975. 68. Edeland HG: Suggestions for a total elasto-dynamic intervertebral disc prosthesis. Biomater Med Devices Artif Organs 9:65–72, 1981. 69. Monson GL, inventor: Synthetic intervertebral disc prosthesis. US patent 4,863,477, September 5, 1989.

Intervertebral disc prosthesis and ..

The intervertebral discs increase in height from cranial to caudal and are mostly higher ventrally than dorsally in the cervical and lumbar spine, thus resulting in a ventrally open intervertebral angle. During the load transfer within an intact intervertebral disc, the nucleus pulposus with its high internal pressure protects the annulus fibrosus against overloading. With its internal pressure, the nucleus pulposus on the one hand maintains the distance between the vertebral bodies, and on the other hand, it firmly holds them together because the pressure acting on the annulus fibrosus strains the lamellae of the fibrous ring going from vertebra to vertebra.1 The nucleus pulposus thus secures the intervertebral distance and the height of the foramina intervertebralia, as well as part of the stability of the FSU.

October 14, 1997. 51. Bisserie M, inventor: Intervertebral disk prosthesis. US patent 5,702,450, December 30, 1997. 52. Bainville D, Laval F, Roy-Camille R, et al, inventors: Intervertebral disk prosthesis. US patent 5,674,294, October 7, 1997. 53. Viart and Marin, French Patent 2895985, 2001. 54. Bao QB, Yuan HA: Prosthetic disc replacement: the future. Clin

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Synthetic intervertebral disc prosthesis: US4874389: 7 Dec 1987: ..

6. Chow DH, Luk KD, Evens JH, Leong JC: Effects of short anterior lumbar interbody fusion on biomechanics of neighboring unfused segments. Spine 21:549–5, 1996. 7. Padua R, Padua S, Aulisa L, et al: Patient outcomes after Harrington instrumentation for idiopathic scoliosis: a 15- to 28-year evaluation. Spine 26:1268–1273, 2001. 8. Ghiselli G, Chen J, Kaou M, et al: Adjacent segment degeneration in the lumbar spine. J Bone Joint Surg 86:1497–1503, 2004. 9. Eck JC, Humphreys SC, Hodges SD: Adjacent-segment degeneration after lumbar fusion: a review of clinical, biomechanical, and radiologic studies. Am J Orthop 28:336–340, 1999. 10. Kostuik JP: Intervertebral disc replacement: Experimental study. Clin

Patente US5458642 - Synthetic intervertebral disc - …

1. Vernon-Roberts B, Pirie CJ: Degenerative changes in the intervertebral discs of the lumbar spine and their sequelae. Rheumatology 16:13–19, 1977. 2. Ibrahim T, Tleyjeh IM, Gabbar O: Surgical versus non-surgical treatment of chronic low back pain: a meta-analysis of randomised trials. Int Orthop Nov. 21, 2006, epub. 3. Lotz JC, Hsieh AH, Walsh AL, et al: Mechanobiology of the intervertebral disc. Biochem Soc Trans 30:853–858, 2002. 4. Aoki Y, Akeda K, An H, et al: Nerve fiber ingrowth into scar tissue formed following nucleus pulposus extrusion in the rabbit anularpuncture disc degeneration model: effects of depth of puncture. Spine 31:E774–E780, 2006. 5. McCarthy PW: Innervation of lumbar intervertebral disks—a review. J Peripher Nerv Syst 3:233–242, 1998.

Finite-Element Modeling of the Synthetic Intervertebral Disc

Orthop Rel Res 337:27–41, 1997. 1. Szpalski M, Gunzburg R, Mayer M: Spine arthroplasty: a historical review. Eur Spine J 1:65–84, 2002. 12. Fernstrom U: Arthroplasty with intercorporal endoprothesis in herniated disc and in painful disc. Acta Chir Scand Suppl 357:154–159, 1966. 13. Charnley J: The long-term results of low-friction arthroplasty of the hip performed as a primary intervention. J Bone Joint Surg Br 54:61–76, 1972. 14. Ibo I, Pierotto E, inventors: Prosthesis of the cervical intervertebralis disk. US patent 5,755,796, May 26, 1998. 15. Graham DV, inventor: Artificial disk. US patent 5,246,458,

Synthetic intervertebral disc - PatentBuddy

Whereas the facet joints are real joints, the intervertebral discs do not have the typical anatomic structures of a joint despite their mobility. Phylogenetically, only a limited morphologic adaptation to the upright human gait took place. This can be seen in physiologic changes to the aging intervertebral discs and the high rate of morbidity of the cervical and lumbar spine worldwide. The closed functional interaction of an intervertebral disc with the facet joints of the same motion segment can be seen in corresponding degenerative changes of the facet joints as a result of degeneration of an intervertebral disc with the decreased height of the intervertebral space. Conversely, a resection of dorsally stabilizing spinal structures, including parts of the facet joints, leads to higher loads and in the long term degeneration of the intervertebral disc at the same level.

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