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American Journal of Polymer Science

205. Huang RQ, Qu YH, Ke WL, Zhu JH, Pei YY, Jiang C. Efficient gene delivery targeted to the brain using a transferrin-conjugated polyethyleneglycol-modified polyamidoamine dendrimer. 2007;4(21):1117-1125

p-ISSN: 2163-1344 e-ISSN: 2163-1352

99. Howard KA, Rahbek UL, Liu X, Damgaard CK, Glud SZ, Andersen MO, Hovgaard MB, Schmitz A, Nyengaard JR, Besenbacher F, Kjems J. RNA interference in vitro and in vivo using a novel chitosan/siRNA nanoparticle system. 2006;4(14):476-484

2014; 4(3):240-255. doi:10.7150/thno.6914

Synthesis of Functionalized NMP Initiators for Click Chemistry: a Versatile Method for the Preparation of Functionalized Polymers and Block Copolymers.

100. Lavertu M, Methot S, Tran-Khanh N, Buschmann MD. High efficiency gene transfer using chitosan/DNA nanoparticles with specific combinations of molecular weight and degree of deacetylation. 2006;27(27):4815-4824

Lian Jin1,*, Xin Zeng2,*, Ming Liu1, Yan Deng1,3, Nongyue He1,3

101. He XK, Yuan ZX, Wu XJ, Xu CQ, Li WY. Low molecular weight hydroxyethyl chitosan-prednisolone conjugate for renal targeting therapy: synthesis, characterization and in vivo studies. 2012;2(11):1054-1063

94. Bozkir A, Saka OM. Chitosan nanoparticles for plasmid DNA delivery: effect of chitosan molecular structure on formulation and release characteristics. 2004;2(11):107-112

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Keywords: Non-viral, Gene delivery, Vectors, Chemical Methods.

105. Sato T, Ishii T, Okahata Y. In vitro gene delivery mediated by chitosan. Effect of pH, serum, and molecular mass of chitosan on the transfection efficiency. 2001;15(22):2075-2080

Primary physical methods for gene delivery.

93. Thanou M, Florea BI, Geldof M, Junginger HE, Borchard G. Quaternized chitosan oligomers as novel gene delivery vectors in epithelial cell lines. 2002;1(23):153-159

Viral systems for gene delivery.

106. Turan K, Nagata K. Chitosan-DNA nanoparticles: the effect of cell type and hydrolysis of chitosan on in vitro DNA transfection. 2006;4(11):503-512

Schematic representation of the structure of liposomes.

107. Sajomsang W, Gonil P, Ruktanonchai UR, Petchsangsai M, Opanasopit P, Puttipipatkhachorn S. Effects of molecular weight and pyridinium moiety on water-soluble chitosan derivatives for mediated gene delivery. 2013;2(91):508-517

The schematic presentation of gene delivery process of polymers.

92. Kean T, Roth S, Thanou M. Trimethylated chitosans as non-viral gene delivery vectors: cytotoxicity and transfection efficiency. 2005;3(103):643-653

Primary applications of chitosan in biomedical fields.

108. Sarkar K, Kundu PP. PAMAM conjugated chitosan through naphthalimide moiety for enhanced gene transfection efficiency. 2013;98(1):495-504

Colloid Interface Sci. 2007, , 491-496.

109. Wang BQ, He CB, Tang C, Yin CH. Effects of hydrophobic and hydrophilic modifications on gene delivery of amphiphilic chitosan based nanocarriers. 2011;20(32):4630-4638

Catalytic Azide-Alkyne Cycloaddition: Reactivity and Applications.

91. Hwang SJ, Bellocq NC, Davis ME. Effects of structure of beta-cyclodextrin-containing polymers on gene delivery. 2001;2(12):280-290

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