Quick academic help
Don't let the stress of school get you down! Have your essay written by a professional writer before the deadline arrives.
optical tweezers open new opportunity to study the material
BM 517 Novel Applications in Biomedical Optics (3+0+0) 3 ECTS 7
(Biyomedikal Optikte Yeni Uygulamalar)
New research studies on bioimaging, confocal and multiphoton microscopy, optical coherent tomography, spectroscopic diagnostics, tissue engineering with light, laser tweezers and scissors, photodynamic therapy and biostimulation.
Optical tweezers use the optical forces generated by a laser to capture, or "tweeze", a micron-sized dielectric particle, such as a polystyrene bead.
Optical tweezers thesis Research paper Service
"The optical tweezers will allow us to directly observe, in real time, the process of gene carrier/DNA complex formation and DNA release at the single molecule level," Seog explains.
Microdissection allows one to select and isolate part of a sample and use it for further studies (RT-PCR, protein analysis, selection of live cells). Laser microdissection can also be used with live samples to study recovery after a cut, protein recruitment after photodamage… The system is paired with optical tweezer to manipulate samples.
Sensors | Sections: Physical Sensors | Editorial Board
Seog, who previously used optical tweezers to explore the mechanical behavior of cell adhesion molecules, plans to apply the technique to further research in nanomedicine and nanobiotechnology.
The optical tweezers will allow Seog and his team to study the earliest interactions between individual proteins that will lead them to form small complexes called oligomers, and then move on to aggregation.
Why choose our assistance?
As soon as we have completed your work, it will be proofread and given a thorough scan for plagiarism.
Our clients' personal information is kept confidential, so rest assured that no one will find out about our cooperation.
We write everything from scratch. You'll be sure to receive a plagiarism-free paper every time you place an order.
We will complete your paper on time, giving you total peace of mind with every assignment you entrust us with.
Want something changed in your paper? Request as many revisions as you want until you're completely satisfied with the outcome.
We're always here to help you solve any possible issue. Feel free to give us a call or write a message in chat.
Faculty - Department of Physics - Sharif
Seog points out that his lab's optical tweezers have two advantages over other most other units: instead of calculating force based on spring constants and displacements, his directly measures force without labor-intensive calibration steps.
Sam's Laser FAQ - Items of Interest
Karcz spent time at the lab with research scientist Steven Smith to learn how to build the tweezers for Seog's Molecular Mechanics Laboratory, as well as create documentation and schematics for it. The Molecular Mechanics Laboratory, directed by Assistant Professor Joonil Seog (joint, Fischell Department of Bioengineering and Department of Materials Science and Engineering), is completing setup of a new optical tweezers unit to be used in studies of protein aggregation, gene delivery and self-assembled biomaterials.
Back to Sam's Laser FAQ Table of Contents
Collagen, the most abundant protein in the body, assembles into an extra-cellular fibrillar gel, which has both viscous and elastic properties. These properties can be determined by using optical tweezers to hold a micron-sized bead within the sample. Measurement of the bead’s thermally induced motion enables the determination of the frequency-dependent viscoelasticity. Rather than only probing response at a single location, holographic optical tweezers create multiple, independent traps, permitting simultaneous tracking of multiple embedded beads and characterization of their correlated motion. By using this technique in a collagen gel, we will be able to determine local and cross-correlated viscoelastic properties, which vary at different locations during its formation. Implications of this research lie in the fields of health and biomaterials. The aim of this work is to devise and validate protocols for using holographic optical tweezers to measure local and through-space viscoelasticity. Rather than using laser deflection to track particle motion, I use a high-speed camera and image analysis to track the simultaneous motion of multiple beads. This approach provides nanometer-scale resolution of particle position at sampling rates up to 2.5 kHz. I compare tracking data collected from the high-speed camera to those collected by the laser deflection method and find a discrepancy in the perceived motion of the bead. I perform many experimental tests to assess the root of this problem. Additionally, I numerically represent bead motion measurements if collected using both methods (laser-deflection method and high-speed camera method) and compare them to the idealized measurement results. In doing so, I learn about the limitations of each method, and how the viscous and elastic properties inferred from the data are affected by each measurement device. Finally, based on my numerical representations, I suggest a simple procedure to gain more accuracy in the viscous and elastic properties for both simple fluids (such as water) and complex fluids (such as collagen solutions) when using each method. This procedure can be used in future holographic optical tweezers-based experiments to obtain an accurate representation of the local and correlated properties of collagen.
How it works
You submit your order instructions
We assign an appropriate expert
The expert takes care of your task
We send it to you upon completion
Average quality score
"I have always been impressed by the quick turnaround and your thoroughness. Easily the most professional essay writing service on the web."
"Your assistance and the first class service is much appreciated. My essay reads so well and without your help I'm sure I would have been marked down again on grammar and syntax."
"Thanks again for your excellent work with my assignments. No doubts you're true experts at what you do and very approachable."
"Very professional, cheap and friendly service. Thanks for writing two important essays for me, I wouldn't have written it myself because of the tight deadline."
"Thanks for your cautious eye, attention to detail and overall superb service. Thanks to you, now I am confident that I can submit my term paper on time."
"Thank you for the GREAT work you have done. Just wanted to tell that I'm very happy with my essay and will get back with more assignments soon."