Quick academic help
Don't let the stress of school get you down! Have your essay written by a professional writer before the deadline arrives.
Synthesis of C-branched spermine tethered oligo-DNA …
Since that time, there have been many different iterations and advancements in synthesis technology, culminating in a further developmental leap in 2017. A major shortcoming of oligo synthesisers was their wear and the frequency of breakdowns with associated down-time. Here, Eurofins Genomics US turned to an unlikely field for the model – aerospace engineering ̶ completely rethinking the DNA manufacturing process and, once again, succeeding in reshaping the marketplace.
Nucleotides are the building blocks of life, and a form of these – oligonucleotides (or oligos) – are short, synthesised DNA strands required by scientists for almost all polymerase chain reaction (PCR)-based research. PCR sees stretches of synthesised DNA (oligo synthesis) amplified by creating a number of identical or near-identical copies and is used in a huge set of basic and applied research applications, across all areas of life science and a whole range of genomic investigations. In most cases, the synthesised oligos are used to determine whether a searched-for DNA sequence is present in a product or biological system.
Synthesise the oligo up to the ..
To engineer its next generation DNA synthesiser, Eurofins Genomics US partnered with a commercial-grade, aerospace engineering company. The result was the production of high-quality oligos in a shorter time. Also, owing to the incredible power and speed of the machine, the Eurofins team raised the ceiling on scalability and volume, its innovative design making the production of even extremely small volumes of DNA affordable.
Building a DNA synthesiser to manufacture these oligos is almost like building a small jet engine – both utilise the science of air pressure, air flow, vibration, fluidics, and thermodynamics, inside complex, mechanical engineering. But it was the adoption of aerospace engineering’s reaction to downtime – the sector considers it unthinkable – that facilitated the greatest step-change.
In Vitro using an oligo synthesiser
Scientists who buy oligos demand several conditions: high quality and reliability, rapid turnaround time, low cost, and the right quantity. Unfortunately, previous DNA synthesis technologies failed to accomplish all of these at once. Traditional high-throughput oligonucleotide synthesisers use a lot of reagents and make more DNA than that required in most applications. By contrast, emerging microarray or chip based methods generate too little DNA that, besides requiring additional downstream work before being useful, is only suitable for specific applications, predominantly, gene synthesis.
Why choose our assistance?
As soon as we have completed your work, it will be proofread and given a thorough scan for plagiarism.
Our clients' personal information is kept confidential, so rest assured that no one will find out about our cooperation.
We write everything from scratch. You'll be sure to receive a plagiarism-free paper every time you place an order.
We will complete your paper on time, giving you total peace of mind with every assignment you entrust us with.
Want something changed in your paper? Request as many revisions as you want until you're completely satisfied with the outcome.
We're always here to help you solve any possible issue. Feel free to give us a call or write a message in chat.
How it works
You submit your order instructions
We assign an appropriate expert
The expert takes care of your task
We send it to you upon completion
Average quality score
"I have always been impressed by the quick turnaround and your thoroughness. Easily the most professional essay writing service on the web."
"Your assistance and the first class service is much appreciated. My essay reads so well and without your help I'm sure I would have been marked down again on grammar and syntax."
"Thanks again for your excellent work with my assignments. No doubts you're true experts at what you do and very approachable."
"Very professional, cheap and friendly service. Thanks for writing two important essays for me, I wouldn't have written it myself because of the tight deadline."
"Thanks for your cautious eye, attention to detail and overall superb service. Thanks to you, now I am confident that I can submit my term paper on time."
"Thank you for the GREAT work you have done. Just wanted to tell that I'm very happy with my essay and will get back with more assignments soon."