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1. To introduce basic concepts of organic synthesis:

The use of such enolate anions from carbonyl compounds is fundamental to organic synthesis and you will already have met them as intermediates in the Aldol reaction and Claisen condensation.

 Palladium-catalyzed reactions of organic halides with olefins , 1979, 12(4), pp 146-151

Abstract. This paper describes the Heck synthesis of ()-4-acetylcinnamic acid from 4-iodoacetophenone and acrylic acid under catalysis by Pd (0). Traditional Heck reaction organic solvents (acetonitrile, -methyl-2-pyrrolidone) and base (triethylamine) are replaced by water and sodium carbonate respectively. This approach introduces fundamentals of green chemistry to undergraduates whilst highlighting current research via an industrially significant reaction.

Also in CCBFR, organometallic compounds are important.

When faced with the challenge of preparing a specific organic compound ho do we go about it?

Elsevier’s new ChemApp is based on the bestselling book Strategic Applications of Named Reactions in Organic Synthesis by László Kürti and Barbara Czakó.

Contemporary Organic Synthesis; The intramolecular Heck reaction

useful compounds in organic synthesis

Intramolecular Imidoylative Heck Reaction: Synthesis …
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