Quick academic help
Don't let the stress of school get you down! Have your essay written by a professional writer before the deadline arrives.
Acute and Chronic Sinusitis - Fauquier ENT
Autoantibodies that develop are selectively directed against the particular cytochrome that metabolized the parent drug. The hapten hypothesis proposes that the drug metabolite can act as a hapten and can modify the self of the individual by covalently binding to proteins. The danger hypothesis proposes that the immune system only responds to a foreign antigen if the antigen is associated with a danger signal, such as cell stress or cell death.Most clinically overt adverse hepatic events associated with drugs are unpredictable, and they have intermediate (1 to 8 weeks) or long latency (up to 12 months) characteristic of reactions.Immune-mediated drug-induced liver nearly always disappears or becomes quiescent when the drug is removed.Exemples methyldopa
minocycline
nitrofurantoinReferences Liu ZX, Kaplowitz N.

Chapter 6 cites two examples in which in-vitro data make it possible to reduce the uncertainties in risk assessment associated with exposure to ozone and ultraviolet radiation.
Adaptive immune system - Wikipedia

Very little is understood about the mechanism of IDRs and their unpredictable nature makes them very difficult to study. There is a large amount of circumstantial evidence that most are and are caused by chemically of the drugs involved rather than to the drug itself. The two major mechanistic hypotheses for these reactions are the and the . The hapten hypothesis is that a drug, or more likely a reactive metabolite of a drug, covalently binds to protein making it "foreign" and in some patients this leads to an immune response. The danger hypothesis is that for something to induce an immune response it has to cause cell damage or cell stress, otherwise it will either be ignored by the immune system or induce tolerance. These two hypotheses are not mutually exclusive.
Lecture Notes in Immunology: Function of the Human


Why choose our assistance?
-
UNMATCHED QUALITY
As soon as we have completed your work, it will be proofread and given a thorough scan for plagiarism.
-
STRICT PRIVACY
Our clients' personal information is kept confidential, so rest assured that no one will find out about our cooperation.
-
COMPLETE ORIGINALITY
We write everything from scratch. You'll be sure to receive a plagiarism-free paper every time you place an order.
-
ON-TIME DELIVERY
We will complete your paper on time, giving you total peace of mind with every assignment you entrust us with.
-
FREE CORRECTIONS
Want something changed in your paper? Request as many revisions as you want until you're completely satisfied with the outcome.
-
24/7 SUPPORT
We're always here to help you solve any possible issue. Feel free to give us a call or write a message in chat.
How it works
-
You submit your order instructions
-
We assign an appropriate expert
-
The expert takes care of your task
-
We send it to you upon completion
Our achievements
-
37 684
Delivered orders
-
763
Professional writers
-
311
Writers online
-
4.8/5
Average quality score