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The process of cholesterol synthesis can be ..
A combination of factors and mechanisms appears to contribute to the cholesterol lowering action of barley. Soluble fiber is suggested to reduce cholesterol by increased excretion of bile acids or neutral sterols, increased catabolism of LDL cholesterol, and reduced absorption of fat. Soluble fibers were shown to be fermented in the colon and thus to give rise to short-chain fatty acids that can be absorbed and may inhibit hepatic cholesterol synthesis. In addition to the soluble fiber, barley contains a wide range of phytochemicals, some of which are being investigated for their effect on metabolism.
Researchers think exercise protects against gallstone disease by reducing known risk factors such as obesity, insulin resistance and serum triglyceride levels.
Hepatic fatty acid synthesis is elevated when plasma insulin ..
Polyphenol-rich dark chocolate and cocoa powder has been shown to reduce LDL cholesterol, increase HDL cholesterol and protect LDL cholesterol from oxidation. The researchers report that eating 100 g of dark chocolate for two weeks reduced blood pressure and LDL cholesterol levels, improved flow-mediated dilation, and ameliorated insulin resistance in patients with hypertension.
Legumes (such as beans, pinto beans, and navy beans) are among the foods found to lower cholesterol. All of the legumes are especially high in soluble fiber. Soluble fiber has been shown to reduce total and low-density lipoprotein cholesterol levels as well as insulin resistance. In addition, legumes are generally low in sodium and rich in minerals such as potassium, calcium, and magnesium. Also, legumes are inexpensive, nutrient-dense sources of plant protein that can be substituted for dietary animal protein.
They work by inhibiting an enzyme involved with cholesterol synthesis
Allicin is the bioactive compound in garlic that inhibits cholesterol synthesis in vitro. However, numerous studies have produced conflicting results regarding garlic's ability to lower blood cholesterol. So, cholesterol lowering potential of garlic remains unproven.
Also left uncovered was the structure, synthesis and differences from lipoproteins, all of which might help your readers understand how to read a CBC or triglyceride / lipoprotein panel when they go in for lab work.
I wonder if you don't want to go into a bit more detail as to why, for example, rapidly absorbed monosaccharides and polyhydroxyl alcohols are a bad idea for folks with elevated triglycerides (acetylation and fat synthesis wouldn't be a bad topic to cover, either).
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Direct Effect of Cholesterol on Insulin Secretion | Diabetes
Most evidence supports that omega-3 fatty acids inhibit hepatic triglyceride synthesis, decrease Very low-density lipoproteins (VLDL) production/secretion and increase VLDL metabolism, potentially increasing the conversion of VLDL particles to LDL particles. Overall, despite a potential increase in LDL cholesterol levels, many studies have reported that omega-3 fatty acids reduces non-HDL cholesterol (total cholesterol minus HDL cholesterol), which may be a better predictor of atherosclerotic coronary heart disease risk than LDL cholesterol alone.
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