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Pruett SB (1992) Immunotoxicity of organophosphorus compounds.

Mengchun Ye, Andrew Edmunds, James Morris, David Sale, Yejia Zhang and Jin-Quan Yu
"A Robust Protocol for Pd(II)-catalyzed C-3 Arylation of (1H)Indazoles and Pyrazoles: Total Synthesis of Nigellidine Hydrobromide"

First octacoordinated double helicate tetraorganotin(IV) compound. Ioana Barbul, Richard A.

Comparative in vivo and in vitro studies with various organotin and organolead compounds in different animal species with special emphasis on lymphocyte cytotoxicity.

Seinen W & Willems MI (1976) Toxicity of organotin compounds.

Membrane-like structure in cell cytoplasm; site of protein synthesis  Endothelium.

The increased susceptibility of rodents to Gram-negative bacteria after exposure to lead is likely to be due to hypersensitivity to an endotoxin of bacterial origin (Cook et al., 1974, 1975) Organolead compounds, such as tetrethyllead, can also be immunotoxic (Luster et al., 1992).

While there is no direct evidence that B and T lymphocytes are the predominant targets of organophosphorus compounds, their mechanisms of action on macrophages are largely unknown.

Direct synthesis of organotin compounds IV. Reaction …

Interestingly, thymus atrophy also occurred in fish, as guppies exposed to organotin compounds showed severe thymic atrophy (Figure 31). Organophosphorus compounds Single doses of the insecticides parathion, malathion, and dichlorvos cause significant reductions in anti-sheep red blood cell plaque-forming cell responses (Casale et al., 1983, 1984).

Thus, after exposure to xenobiotic compounds that destroy the immune system, regeneration can occur within a relatively short time: The original architecture is restored within three to four weeks after involution caused by radiation or treatment with glucocorticosteroid or organotin compounds.

M.; Yu, J.-Q.
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Direct Synthesis of Organotin Compounds. III. Reaction …

Hodge VF, Seidel SL, Goldberg ED (1979) Determination of tin(IV) and organotin compounds in natural waters, coastal sediments and macro algae by atomic absorption spectrometry. , 51(8):1256–1259.

Direct Synthesis of Organotin Compounds

Maguire RJ, Tkacz RJ, Chau YK, Bengert GA, Wong PTS, Chau YK, Kramar O, Bengert GA (1986) Occurrence of organotin compounds in water and sediment in Canada. , 15:253–274.

Direct synthesis of organotin compounds. IV. Reaction …

Chmielnicka J, Zareba G, Grabowska U (1992) Protective effect of zinc on heme biosynthesis disturbances in rabbits after administration per os of tin. , 24:266–274.

Method for the direct synthesis of organotin compounds and their use.

Sensitivity of cell populations in the thymus to toxic chemicals Cells Location Compound Lymphocytes Immature lymphoblasts Outer cortex Some organotin compounds, 2,3,7,8-tetrachlorodibenzo-para-dioxin Small cells Cortex Glucocorticosteroids, cytostatic drugs (e.g.

Organotin compounds in the environment — an …

The most sensitive test results were 72-h exposures to diatoms and embryo-larval amphibian studies, with toxic effects seen at 0.1 to 0.2 mg/litre for tin(II). Even at these concentrations, toxic effects caused by inorganic tin are unlikely, even near sources of local pollution. It should be noted that where concentrations are expressed as total tin, a percentage is likely to be in the form of organotins, such as tributyltin, which are more bioavailable and toxic. For more information on the environmental fate and toxicity of tributyltin, please refer to IPCS (1990, 1999).

Synthesis routes for organotin compounds (from Blunden and ..

Convincing evidence for immunotoxicity has been obtained only for O,O,S-trimethylphosphorothiate ( O,O,S-TMP), a contaminant of various commercial organophosphorus formulations, such as malathion, fenitrothion, and acephate.

the IC 50 values found for the organotin compounds ..

E.; Yu, J.-Q
"Palladium-Catalyzed Alkylation of Aryl C-H Bonds with sp3 Organotin Reagents Using Benzoquinone as a Crucial Promoter"

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