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Toxic effects of aluminium in the skeleton

In a multi-variate analysis, which adjusted for a variety of confounding factors, the adjusted odds ratio for high aluminium level (> 85 µg/litre) was 1.72 (1.08-2.75).

EVALUATION OF HUMAN HEALTH RISKS AND EFFECTS ON THE ENVIRONMENT

The commercial deposits of bauxite are mainly gibbsite (Al2O3Ê3H2O) and boehmite (Al2O3ÊH2O).

Evaluation of effects on the environment

CONCLUSIONS AND RECOMMENDATIONS FOR PROTECTION OF HUMAN HEALTH AND THE ENVIRONMENT

The authors stated that aluminium oxide was the most likely cause for the development of interstitial fibrosis in these workers and that asbestos could be ruled out.

In a report of nine cases of workers exposed to aluminium oxide (mean duration of exposure 25 years), abnormal chest roentgenograms were described, as well as pathological lung functions in three of the cases (Jederlinic et al., 1990).

Recommendations for protection of the environment

The EHC monographs have become widely established, used and recognized throughout the world.

However, in the mixing zone, between 1 and 3 min after mixing (pH 5.8-5.9; inorganic monomeric Al 78-111 µg/litre), both species gave an LT50 of 7 h.

(1992) exposed in situ caged smolts of Atlantic salmon ( Salmo salar) and sea trout ( Salmo trutta) to waters in an acid tributary (pH 4.8; inorganic monomeric aluminium 236 µg/litre) and the mixing zone with the limed river Audna (Norway) (pH 7.0; inorganic monomeric aluminium 17 µg/litre).

As such, they include and review studies that are of direct relevance for the evaluation.
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Content The layout of EHC monographs for chemicals is outlined below.

This fact, coupled with the large reservoir of aluminium in soils and sediments, means that aluminium concentrations can be substantially enhanced in acidic or poorly buffered environments subjected to sustained or periodic exposure to strong acidifying inputs.

They are required to sign a conflict of interest statement.

However, the solubility of aluminium is highly dependent on pH, increasing at both low and high pH values, which reflects the amphoteric nature of the element.

Such a procedure ensures the transparency and probity of the process.

Elevated concentrations of inorganic monomeric aluminium have detrimental biological effects that are mitigated in the presence of organic acids, fluoride, silicate, and high concentrations of calcium and magnesium.

Becking, IPCS, welcomed the participants on behalf of Dr M.

Aluminium-bearing solid phases are relatively insoluble, particularly in the circumneutral pH range, and so most natural waters contain low concentrations of dissolved aluminium.

The first draft was prepared under the coordination of Dr G.

In one large study of miners exposed to aluminium powder, the difficulties in adequately controlling for confounding factors also lead to much uncertainty in accepting the positive effects observed on cognition.

It is often alloyed with other metals.

However, owing to the small cohorts used in some studies, methodological deficiencies in most studies, and conflicting results from different studies, there is considerable uncertainty in ascribing a causative role for aluminium in the neurological effects reported.

Of these, food is the principal contributor.

This disorder is considered to be irritant-induced following exposure during the production of compounds such as aluminium sulfate, aluminium fluoride and potassium aluminium tetrafluoride, or in production areas of primary aluminium smelting.

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